🧬 Telomere AI

Free, open-source genetic analysis platform. Your DNA never leaves your device.

Analyze your 23andMe, AncestryDNA, MyHeritage, or VCF data directly in your browser at telomere.ai — or download the desktop app for fully offline use.

Website • Download • Build from Source

Why Telomere AI?

Features

• 6 Report Categories — Health risks, longevity/aging, nutrigenomics, pharmacogenomics, physical traits, carrier status
• 378+ Curated SNPs — Real clinical data from ClinVar, PharmGKB, and peer-reviewed GWAS studies
• All Major Formats — 23andMe, AncestryDNA, MyHeritage CSV, VCF 4.x
• Browser or Desktop — Use at telomere.ai instantly, or download the desktop app for offline use
• Zero Network Access — All analysis happens locally. Your genetic data never leaves your device.
• Polygenic Risk Scores — Offline PGS calculator with bundled scoring files

Download

Grab the latest release for your platform:

How It Works

1. Open your raw data file — Download it from your genetic testing provider
2. Instant local analysis — Rust engine parses your SNPs and matches against our curated database
3. Explore your reports — Browse findings by category, search by gene or rsID, see population frequencies

Your genetic data never leaves your computer. The app works fully offline.

Building from Source

Prerequisites

• Rust (latest stable)
• Node.js 22+
• pnpm 9+
• Platform-specific Tauri dependencies: see Tauri docs

Steps

# Clone
git clone https://github.com/vaionex/telomere.ai.git
cd telomere.ai

# Install JS dependencies
pnpm install

# Run in development mode
pnpm tauri:dev

# Build release
pnpm tauri:build

The built app will be in src-tauri/target/release/bundle/.

Project Structure

telomere.ai/
├── apps/web/                 # SvelteKit frontend (Svelte 5)
│   ├── src/routes/           # Pages: landing, upload, dashboard, reports, SNP explorer
│   ├── src/lib/components/   # DnaHelix, FileUpload, SnpCard, RiskGauge, ChromosomeMap
│   └── src/lib/stores/       # Svelte stores for genetic data and reports
├── packages/
│   ├── parsers/              # Genetic file format parsers (JS)
│   ├── snp-db/               # Curated SNP reference database (257+ entries)
│   └── pgs/                  # Polygenic risk score calculator
├── src-tauri/                # Tauri 2 + Rust backend
│   └── src/
│       ├── parser.rs         # Native file parsers (23andMe, Ancestry, VCF, MyHeritage)
│       ├── snp_database.rs   # 155+ SNPs embedded in Rust
│       └── analyzer.rs       # Genotype analysis and risk assessment
├── scripts/                  # Database expansion tools
└── Dockerfile                # Web deployment (marketing site)

SNP Database

Our database includes 257+ SNPs with real, accurate clinical data:

• Longevity — TERT, TERC, FOXO3, APOE, CETP, IL6, SOD2
• Health — 9p21 (CAD), TCF7L2 (T2D), Factor V Leiden, BRCA, HLA-DQ2
• Pharmacogenomics — CYP2D6, CYP2C19, CYP1A2, VKORC1, SLCO1B1, DPYD
• Nutrigenomics — MTHFR, MCM6 (lactose), ALDH2, FTO, VDR, HFE
• Traits — HERC2 (eye color), MC1R (red hair), ACTN3 (muscle), TAS2R38 (taste)
• Carrier — CFTR (cystic fibrosis), HBB (sickle cell), GJB2 (hearing)

Every entry includes risk/normal alleles, population frequencies, conditions, recommendations, and PubMed references.

Expanding the Database

# Add more curated SNPs
node scripts/expand-snp-db.js

Contributing

Contributions welcome! Some areas where help is needed:

• More SNPs — Add clinically validated SNPs with real data
• Polygenic scores — Bundle pre-downloaded PGS Catalog scoring files
• Localization — Translate reports and UI
• Accessibility — Screen reader support, keyboard navigation
• Testing — Unit tests for parsers and risk assessment

Please open an issue first for major changes.

Medical Disclaimer

Telomere AI is for educational and informational purposes only. It is not a medical device and should not be used for diagnosis, treatment, or prevention of any disease. Having a risk allele does not mean you will develop a condition. Always consult with a qualified healthcare professional or genetic counselor for medical advice.

Privacy

• Your genetic data is processed entirely on your computer
• The app never connects to the internet
• No accounts, no uploads, no analytics, no tracking
• Fully auditable — every line of code is in this repository

License

MIT — see LICENSE

Credits

Built by Vaionex Corporation.

SNP data sourced from:

• ClinVar (NCBI)
• PharmGKB
• GWAS Catalog
• Peer-reviewed publications (PubMed references included per SNP)